Acetylcholine Receptor Binding Antibody (AcHR)


Myasthenia Gravis (MG) is an autoimmune neuromuscular disorder characterized by muscle weakness, most commonly due to autoantibody-mediated loss of functional acetylcholine receptors (AChR) in the neuromuscular junction. AChR binding autoantibodies are diagnostic of MG, and are found in 85-90% of MG patients. This assay aids in the differential diagnosis of conditions with MG-like muscle weakness and in monitoring therapeutic response. If binding antibodies are negative, assays for modulating and blocking antibodies should be considered.

Acetylcholine Receptor Binding Antibody (AcHR)


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  • Fasting Required: NO
  • Preferred Specimen: Serum
  • Patient Preparation: None
  • Reference Range(s):
  • Negative ≤0.30 nmol/L
    Equivocal 0.31-0.49 nmol/L
    Positive ≥0.50 nmol/L
  • Turnaround Time: 3 Days
  • Test Code: 206