C-Peptide Response to Glucose, 9 Specimens


C-Peptide is useful in the evaluation of pancreatic beta cell function (e.g., helping distinguish type 1 from type 2 diabetes mellitus, or monitoring patients who have received islet cell or pancreatic transplants) and for determining the source of insulin in patients with hyperinsulinemic hypoglycemia. (e.g., distinguishing insulin-secreting tumors from exogenous insulin administration). It is also sometimes measured as an additional means (more resistant to hemolysis than is insulin itself) for evaluating glucose tolerance tests. 

C-Peptide Response to Glucose, 9 Specimens


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  • Fasting Required: Yes 12 Hours
  • Preferred Specimen: Serum
  • Reference Range(s):
    Fasting: 0.80-3.85 ng/mL
    30 minutes post glucose: 1.78-7.49 ng/mL
    60 minutes post glucose: 1.91-8.21 ng/mL
    90 minutes post glucose: 1.52-7.95 ng/mL
    120 minutes post glucose: 1.19-6.04 ng/mL
    150 minutes post glucose: 1.06-5.98 ng/mL
    180 minutes post glucose: 1.06-3.88 ng/mL
    240 minutes post glucose: 0.86-3.22 ng/mL
    300 minutes post glucose: 0.86-2.50 ng/mL
  • Limitations: CA 19-9 is absent in individuals with blood group Lewis Le(a-b-), as observed in approximately 5% of Caucasian and 20-25% of African American patients. CA 19-9 levels, regardless of value, should not be interpreted as absolute evidence of the presence or absence of disease, more testing may be needed.
  • Turnaround Time: 3 Day
  • Test Code: 15448