VMA (Vanillylmandelic Acid), 24-Hour Urine


Vanillylmandelic acid (VMA) is the major urinary product resulting from the metabolic degradation of catecholamine, norepinephrine and epinephrine. Elevated concentrations of VMA are commonly found in cases of catecholamine secreting tumors such as pheochromocytoma, neuroblastoma, and ganglioneuroma.

Drugs which can interfere with testing due to physiologic response: clonidine, L-dopa, methocarbamol, monoamine oxidase inhibitors, reserpine, salicylates.

VMA (Vanillylmandelic Acid), 24-Hour Urine


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  • Fasting Required: NO
  • Preferred Specimen: 24 Hr Urine
  • Reference Range(s):
    3-8 Years ≤2.3 mg/24 h
    9-12 Years ≤3.4 mg/24 h
    13-17 Years ≤3.9 mg/24 h
    >17 Years ≤6.0 mg/24 h
  • Limitations: Requires accurate 24-hour urine collection.
  • Turnaround Time: 3 Days
  • Test Code: 934