Aldosterone

Description

 

The Aldosterone test is a crucial diagnostic tool used by doctors to evaluate adrenal gland function and investigate conditions that affect blood pressure and electrolyte balance. Aldosterone is a hormone produced by the adrenal glands, located above the kidneys, and plays a key role in regulating sodium and potassium levels in the blood, as well as maintaining healthy blood pressure. When aldosterone levels are too high or too low, it can lead to serious health issues, which is why doctors rely on this test to get valuable insights into a patient's hormonal and cardiovascular health. Here are the primary reasons why a doctor would order an Aldosterone test.

Diagnosing Primary Aldosteronism (Conn’s Syndrome)

One of the main reasons a doctor orders an aldosterone test is to diagnose primary aldosteronism, also known as Conn’s syndrome. This condition occurs when the adrenal glands produce too much aldosterone, leading to high blood pressure (hypertension) and low potassium levels (hypokalemia). Patients with primary aldosteronism may experience symptoms such as fatigue, muscle weakness, excessive thirst, and frequent urination. The aldosterone test helps confirm the diagnosis, guiding doctors to appropriate treatment options such as medication or surgery to remove an adrenal tumor.

Evaluating Adrenal Gland Function

The aldosterone test is also used to assess overall adrenal gland function. The adrenal glands are responsible for producing several hormones, including aldosterone, cortisol, and adrenaline, that regulate various bodily functions. Doctors may order this test if they suspect a disorder of the adrenal glands, such as adrenal hyperplasia (overgrowth of adrenal tissue) or adrenal insufficiency, where the glands do not produce enough hormones. Monitoring aldosterone levels can provide important information about how well the adrenal glands are functioning and whether they are producing hormones in the correct amounts.

Investigating the Causes of High Blood Pressure

Doctors frequently use the aldosterone test when investigating the underlying causes of high blood pressure that is resistant to conventional treatments. Elevated aldosterone levels can cause the body to retain sodium, leading to increased blood volume and, consequently, higher blood pressure. This test helps pinpoint whether hormonal imbalances, such as excess aldosterone production, are contributing to the patient’s hypertension. By identifying hormone-related hypertension, doctors can tailor treatment to target the root cause, rather than just managing symptoms with general blood pressure medications.

Diagnosing Low Aldosterone Levels (Hypoaldosteronism)

In addition to diagnosing conditions related to excess aldosterone, this test is also used to identify hypoaldosteronism, a condition in which the adrenal glands do not produce enough aldosterone. This can lead to low blood pressure, high potassium levels, and symptoms like dizziness, salt cravings, and dehydration. Hypoaldosteronism is often associated with Addison’s disease, an autoimmune disorder where the adrenal glands are damaged. By measuring aldosterone levels, doctors can determine if insufficient aldosterone production is causing the patient’s symptoms and guide treatment decisions, such as hormone replacement therapy.

Assessing Electrolyte Imbalances

Since aldosterone plays a key role in regulating sodium and potassium levels, doctors may order an aldosterone test to investigate electrolyte imbalances. Abnormal levels of sodium or potassium in the blood can lead to various symptoms, including muscle cramps, weakness, or irregular heartbeats. This test helps doctors determine whether abnormal aldosterone levels are contributing to these imbalances and helps guide treatment to restore proper electrolyte balance.

Importance

The Aldosterone test is an essential diagnostic tool for doctors assessing adrenal gland function, diagnosing conditions like primary aldosteronism and hypoaldosteronism, and investigating the causes of high blood pressure and electrolyte imbalances. By measuring aldosterone levels, doctors can identify hormonal imbalances that affect a patient's cardiovascular and metabolic health, allowing for more targeted and effective treatments. For patients with unexplained hypertension or electrolyte disturbances, the aldosterone test is a key step toward accurate diagnosis and improved health outcomes.

Aldosterone

$89

Average competitors price

$199

Pricing based on average direct to consumer pricing.

 

Reference Range(s)

Adult

 

Upright 8:00-10:00 am

≤28 ng/dL

Upright 4:00-6:00 pm

≤21 ng/dL

Supine 8:00-10:00 am

3-16 ng/dL

Pediatric

 

1-12 months**

2-70 ng/dL

1-4 years**

2-37 ng/dL

5-9 years

≤9 ng/dL

10-13 years

≤21 ng/dL

14-17 years

≤35 ng/dL

Infants

 

Premature (31-35 weeks)**

≤144 ng/dL

Term**

≤217 ng/dL

Tanner Stages**

 

II-III Males

1-13 ng/dL

II-III Females

2-20 ng/dL

IV-V Males

3-14 ng/dL

IV-V Females

4-32 ng/dL

 

Preferred Specimen(s)

1 mL serum collected in a red-top tube (no gel)

 

Resulting Lab: Quest Diagnostics

Draw Site: Quest PSC

Fasting Required: No

Preferred Specimen: Serum

Turnaround Time: 4 days

Test Code: 17181