Testing Details
The Beta-2-Glycoprotein I Antibodies test (IgG, IgA, IgM) is used to detect immune system antibodies that target beta-2-glycoprotein I, a protein involved in blood clot regulation. This test helps identify antiphospholipid syndrome (APS), a condition that increases the risk of abnormal blood clots, miscarriages, and autoimmune disorders.
Doctors use this test to:
- Diagnose or rule out APS
- Evaluate unexplained blood clots (DVT, stroke, PE)
- Investigate recurrent pregnancy loss
- Monitor autoimmune diseases like lupus
It measures all three antibody types — IgG, IgA, and IgM — providing a full picture of the immune response. This makes the test especially valuable for individuals with suspected autoimmune clotting disorders or those at risk of APS-related pregnancy complications.
Symptoms that may warrant this test include clotting events without clear cause, chronic fatigue, low platelet count, or autoimmune markers such as joint pain or rashes.
The Beta-2-Glycoprotein I Antibodies test helps guide treatment decisions, including anticoagulants or pregnancy monitoring, and can prevent serious complications when detected early.
